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N-Acetyl Linaclotide Impurity

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Description

Chemical Name: ((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-Acetamido-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-48,50-dimercapto-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-propanopyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carbonyl)-L-tyrosine

Shipping Temperature:
Ambient

HSN Code:
38229010

Country of Origin: India

Smiles: OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@@H](NC(CNC([C@H]([C@H](O)C)NC([C@@](C(CC2S)S)([H])NC([C@H](C)NC([C@@](CCC3)([H])N3C([C@H](CC(N)=O)NC([C@]4([H])CSSC[C@H](NC(C)=O)C(N[C@]2([H])C(N[C@@H](CCC(O)=O)C(N[C@H]5CC6=CC=C(O)C=C6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CSSC[C@](C(N4)=O)([H])NC5=O)=O

Additional Information

N-Acetyl Linaclotide Impurity is chemically ((3S,6R,9S,15R,20R,23S,26S,29R,32R,37R,40S,45aS)-32-Acetamido-40-(2-amino-2-oxoethyl)-26-(2-carboxyethyl)-23-(4-hydroxybenzyl)-9-((R)-1-hydroxyethyl)-48,50-dimercapto-3-methyl-1,4,7,10,13,22,25,28,31,38,41,47-dodecaoxotetracontahydro-19H-37,20-(epiminomethano)-6,29-propanopyrrolo[2,1-s][1,2,27,28]tetrathia[5,8,11,14,17,20,23,32,35,38,41]undecaazacyclotritetracontine-15-carbonyl)-L-tyrosine.
N-Acetyl Linaclotide Impurity is supplied with detailed characterization data compliant with regulatory guideline. N-Acetyl Linaclotide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Linaclotide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ISP Standards products are for analytical purpose only and not for human use.

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